Biology and genomics of human hair follicles: Research on androgenetic alopecia has shown that it is a very common disease
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Overview of androgenic alopecia
Androgenic alopecia is a common disease that mainly affects men. Its characteristics are complex, related to aging, genetics, and various other factors such as lifestyle.
The problems faced
Although the disease is common, the underlying biological principles are not easily understood, which hinders progress in its treatment.
Research Review Content
Hair follicle related: Reviewed the functional anatomical structure of hair follicles and the cellular signaling events that play a role in hair follicle circulation.
Pathology and Molecular Mechanisms: Discussed the pathology of androgenetic alopecia and the known molecular mechanisms behind it.
Research on transcriptional differences in hair follicles: This study describes the comparative analysis of transcriptional differences in hair follicles between bald and non bald scalp regions.
Risk variation exploration: Considering the contribution of genetic factors, the most important risk variations associated with androgenic alopecia were discussed.
Research prospects
Propose to use multi omics methods to gain a more comprehensive understanding of this pathology, providing a better foundation for further research and treatment of the disease.
The current effective solution is 3% minoxidil solution for treating male androgenic alopecia, but research has shown that 0.25% finasteride combined with 3% minoxidil local solution is more effective and safe than 3% minoxidil solution in treating male androgenic alopecia.
Androgenic alopecia is a common disease that mainly affects men. Its characteristics are complex, related to aging, genetics, and various other factors such as lifestyle.
The problems faced
Although the disease is common, the underlying biological principles are not easily understood, which hinders progress in its treatment.
Research Review Content
Hair follicle related: Reviewed the functional anatomical structure of hair follicles and the cellular signaling events that play a role in hair follicle circulation.
Pathology and Molecular Mechanisms: Discussed the pathology of androgenetic alopecia and the known molecular mechanisms behind it.
Research on transcriptional differences in hair follicles: This study describes the comparative analysis of transcriptional differences in hair follicles between bald and non bald scalp regions.
Risk variation exploration: Considering the contribution of genetic factors, the most important risk variations associated with androgenic alopecia were discussed.
Research prospects
Propose to use multi omics methods to gain a more comprehensive understanding of this pathology, providing a better foundation for further research and treatment of the disease.
The current effective solution is 3% minoxidil solution for treating male androgenic alopecia, but research has shown that 0.25% finasteride combined with 3% minoxidil local solution is more effective and safe than 3% minoxidil solution in treating male androgenic alopecia.